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副教授
贾潇凌

职称职务:副教授,博士生导师
办公地点:5号楼202
E-mail:jiaxiaoling@buaa.edu.cn
 

贾潇凌,副教授,博士生导师。主持国家自然岳的水深又滑又多基金面上项目4项,教育部青年教师基金1项,山西省自然岳的水深又滑又多青年基金1项。作为项目组骨干成员参与国家重点研发计划、国家自然岳的水深又滑又多基金创新岳的水深又滑又多群体项目等多项。以第一作者、通讯作者在国际学术刊物Biomaterials, Acta biomaterialia, Mater Sci Eng C Mater Biol Appl, Pflugers Arch, J Cell Physiol, Cell Prolif等发表多篇学术论文

岳的水深又滑又多方向

1 血管组织工程

2 离子通道在物理因素调控细胞生理病理功能中的作用机制

教育与工作经历

1988.9 - 1992.7

山西大学生物系

生物专业、学士

1992.9 - 1995.7

山西大学生物系

动物专业、硕士

1995.9 - 2003.3

中国辐射防护岳的水深又滑又多院

助理岳的水深又滑又多员

2003.4 - 2007.7

中国岳的水深又滑又多院力学岳的水深又滑又多所

生物力学、博士

2007.9 至今

北京航空航天大学

生物与医学工程学院

讲师、副教授

2002.12 - 2003.3

香港中文大学生物医学学院

访问学者

2019.7 - 2020.7

英国利兹大学生物医学学院 

访问学者

 

主要社会兼职

中国生物医学工程学会                                    会员

中国神经岳的水深又滑又多学会                                        会员

Frontiers in Pharmacology Ion channels     Associate editor (副主编)

 

主要教学获奖

北航第十五届我爱我师十佳教师

 

主持科研项目

1. Piezo1BKCaIKCa在牵张调控血管平滑肌细胞功能中的协同作用及机制,国家自然岳的水深又滑又多基金面上项目,2023.01-2026.1255万。

2. CaveolaeTRPC1-SOCE的影响在周期性牵张调控血管平滑肌细胞增殖、迁移中的作用及机制岳的水深又滑又多,国家自然岳的水深又滑又多基金面上项目,2019.01-2022.1263

3. IKCa通道在周期性牵张调控血管平滑肌细胞表型转变、增殖、迁移中的作用及机制岳的水深又滑又多,国家自然岳的水深又滑又多基金面上项目,2014.01-2018.1290万。

4. 切应力对血管平滑肌细胞BKCa通道的影响及Beta1 Beta3 整合素在其中所起的作用,国家自然岳的水深又滑又多基金面上项目,2010.01-2012.1244万。

5. 炎症介质刺激下白细胞表面L-选择素的表达、分布和动力学变化的岳的水深又滑又多,教育部青年教师基金, 2009.01-2011.123.6万。

  

主要论著

1. Xiaoling JiaXinlan ChenChao Gaoet al. Functional cooperation between IKCa and TRPC1 channels regulates serum-induced vascular smooth muscle cell proliferation via mediating Ca2+ influx and ERK1/2 activation. Cell Prolif  2022 23;e13385.

2. Philippa MalkoXiaoling JiaIan Wood, Lin-Hua Jiang. Piezo1 channel-mediated Ca2+ signaling inhibits lipopolysaccharide-induced activation of the NF-κB inflammatory signaling pathway and generation of TNF-αand IL-6 in microglial cells. Glila. 2022. doi: 10.1002/glia.24311.

3. Xiaoling Jia, Qingmao Yang, Chao Gao, et al. Stimulation of vascular smooth muscle cell proliferation by stiff matrix via the IKCa channel‐dependent Ca2+ signaling. J Cell Physiol . 2021;236(10):6897-6906.

4. Xiaoling Jia, Chao Gao, Xia Wang, et al. Differential regulation by mechanical stretch of the expressions of large‑conductance Ca2+‑activated K+ channel and L‑type voltage‑dependent Ca2+ channel in rat uterine smooth muscle cells. J Membr Biol. 2022;255(2-3):357-361.

5. Xiaoling JiaHao SuXinlan Chenet al. A critical role of the KCa3.1 channel in mechanical stretch-induced proliferation of rat bone marrow-derived mesenchymal stem cells. J Cell Mol Med. 2020 ;24(6):3739-3744.

6. Yang Yang, Qingmao Yang, Fang Zhou, Yunhui Zhao, Xiaoling Jia*, Xiaoyan Yuan, Yubo Fan. Electrospun PELCL membranes loaded with QK peptide for enhancement of vascular endothelial cell growth. J Mater Sci Mater Med. 2016 ;27(6):106.                              co-correspondence

7. Fang Zhou, Xiaoling Jia#, Qingmao Yang, et al. Targeted delivery of microRNA-126 to vascular endothelial cells via REDV peptide modifified PEG-trimethyl chitosan. Biomater Sci 2016 May 26;4(5):849-56. co-first

8. Fang ZhouXiaoling Jia#Yang Yanget al. Nanofiber-mediated microRNA-126 delivery to vascular endothelial cells for blood vessel regeneration. Acta Biomater. 2016 ;43:303-313.                                      co-first

9. Zhou Fang, Xiaoling Jia#, Yang Y, et al. Peptide-modifified PELCL electrospun membranes for regulation of vascular endothelial cells. Mater Sci Eng C Mater Biol Appl. 2016 ;68:623-631.                              co-first

10. Jie Fan, Xiaoling Jia, Yan Huang, et al. Greater scaffold permeability promotes growth of osteoblastic cells in a perfused bioreactor. J Tissue Eng Regen Med. 2015;9(12):E210-8.

11. Xufeng NiuPin ChenXiaoling Jiaet al. Microencapsulation of mechano growth factor E peptide for sustained delivery and bioactivity maintenance. Int J Pharm. 2014;469(1):214-21.

12. Hong Zhang, Xiaoling Jia#, Fengxuan Han, et al. Dual-Delivery of VEGF and PDGF by Double-layered Electrospun Membranes for Blood Vessel Regeneration. Biomaterials. 2013;34(9): 2202-2212.                       co-first

13. Fengxuan Han, Xiaoling Jia#, D Dai, et al. Performance of a multilayered small-diameter vascular scaffold dual-loaded with VEGF and PDGF. Biomaterials. 2013;34(30): 7302-7312.                                  co-first  

14. Xiaoling Jia, Jingyun Yang, Wei Song, et al. Involvement of large conductance Ca2+-activated K+ channel in laminar shear stress-induced inhibition of vascular smooth muscle cell proliferation. pflugers archiv-european journal of physiology 2013;465:221-232.

15. Meiliang Li, Xiaoling Jia#, Jingyun Yang , et al. Effect of tannic acid on properties of soybean seed ferritin: A model for interaction between naturally -occurring components in foodstuffs. Food Chemistry 2012;133:410-415 co-first

16. Xiaoling Jia, Chenguang Zhao, Ping Li, et al. Sustained release of VEGF by coaxial electrospun dextran/PLGA fibrous membranes in vascular tissue engineering. Journal of biomaterial science-polymer edition. 2011;22:1811-1827.

17. Chenyan Lv, Xiaoling Jia#, Meiliang Li, et al. Optimization of extraction process of crude protein from grape seeds by RSM. Food Sci and Technol Res  2011;17:437-445. Co-first                                 co-first

18. Yan Huang, Xiaoling Jia, Ke Bai, et al. Effects of fluid shear stress on cardiomyogenic differentiation of rat bone marrow mesenchymal stem cells. Arch Med Res 2010 ;41(7):497-505.

19. Ping Li, Feng X, xiaoling Jia, Yubo Fan. nfluences of tensile load on in vitro degradation of an electrospun poly(L-lactide-co-glycolide) scaffold. Acta Biomater. 2010;6(8):2991-2996.

20. Xin Gu, Xiaoling Jia#, Jiannan Feng, et al. Molecular modeling and affinity determination of scFv antibody: proper linker peptide enhances its activity. Ann Biomed Eng. 2010, 38:537-549.                             co-first

21. Xiaoling Jia, Juan Chen and Mian Long. IL-8-induced L-selectin shedding regulates its binding kinetics to PSGL-1. Chinese Science Bulletin. 2009,54:2787-2793.

22. Mian Long, Xiaoling Jia. Selectin shedding regulates two-dimensional binding to PSGL-1. Biorheology 2008, 45:74-75.

23. Li Wu, Botao XiaoXiaoling Jiaet al. Impact of carrier stiffness and microtopology on two-dimensional kinetics of P-selectin and P-selectin glycoprotein ligand-1 interactions. Journal of biological chemistry 2007, 282:9846-9854